Maildramon chased Calumon through a digital area between the digital world and Earth, intending to kill him. However, he was intercepted by DarkTyrannomon, who fought her. Maildramon nearly killed DarkTyrannomon, until he digivolved to MetalTyrannomon and killed Maildramon by stomping on her.
Maildramon is shown to be sadistic as she tries to kill an extremely cute and defenseless Digimon.
- Maildramon is the first character in Digimon Tamers to die.